STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASZ1Castor zinc finger 1. (1643 aa)    
Predicted Functional Partners:
ISOC1
Isochorismatase domain containing 1.
      
 0.720
RASGEF1C
RasGEF domain family member 1C.
      
 0.664
LIX1
Limb and CNS expressed 1.
      
 0.653
CCAR1
Cell division cycle and apoptosis regulator 1.
      
 0.614
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
      
 0.613
ADGRE3
Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family.
      
 0.612
PLCH1
Phosphoinositide phospholipase C.
      
 0.562
OTOF
Otoferlin.
      
 0.541
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
 
 0.538
CSRNP1
Cysteine and serine rich nuclear protein 1.
      
 0.535
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.