STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RND2Rho family GTPase 2. (233 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.951
ITSN1
Intersectin 1.
    
 0.915
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.871
PLXNB3
Plexin B3.
    
 0.864
PLXNB1
Plexin B1.
    
 0.827
RRAS
RAS related.
  
 
 0.823
PLXNA1
Plexin A1.
    
 0.763
MYO9B
Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.739
MYO9A
Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.739
SEMA4D
Semaphorin 4D; Belongs to the semaphorin family.
    
 0.738
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.