| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS1 | ADSS2 | ENSOARP00000008262 | ENSOARP00000005975 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS1 | ALDH18A1 | ENSOARP00000008262 | ENSOARP00000006765 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.672 |
| ADSS1 | ASNS | ENSOARP00000008262 | ENSOARP00000005016 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.930 |
| ADSS1 | ASRGL1 | ENSOARP00000008262 | ENSOARP00000015884 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Asparaginase and isoaspartyl peptidase 1. | 0.910 |
| ADSS1 | ASS1 | ENSOARP00000008262 | ENSOARP00000008253 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Argininosuccinate synthase 1. | 0.944 |
| ADSS1 | CAD | ENSOARP00000008262 | ENSOARP00000020648 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.943 |
| ADSS1 | GOT1 | ENSOARP00000008262 | ENSOARP00000013317 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Aspartate aminotransferase. | 0.925 |
| ADSS1 | GOT1L1 | ENSOARP00000008262 | ENSOARP00000001090 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.925 |
| ADSS1 | GOT2 | ENSOARP00000008262 | ENSOARP00000001804 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Aspartate aminotransferase. | 0.925 |
| ADSS1 | NAT8L | ENSOARP00000008262 | ENSOARP00000016720 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | N-acetyltransferase domain-containing protein. | 0.900 |
| ADSS2 | ADSS1 | ENSOARP00000005975 | ENSOARP00000008262 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.901 |
| ADSS2 | ALDH18A1 | ENSOARP00000005975 | ENSOARP00000006765 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.672 |
| ADSS2 | ASNS | ENSOARP00000005975 | ENSOARP00000005016 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.949 |
| ADSS2 | ASRGL1 | ENSOARP00000005975 | ENSOARP00000015884 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparaginase and isoaspartyl peptidase 1. | 0.908 |
| ADSS2 | ASS1 | ENSOARP00000005975 | ENSOARP00000008253 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate synthase 1. | 0.944 |
| ADSS2 | CAD | ENSOARP00000005975 | ENSOARP00000020648 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.943 |
| ADSS2 | GOT1 | ENSOARP00000005975 | ENSOARP00000013317 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.925 |
| ADSS2 | GOT1L1 | ENSOARP00000005975 | ENSOARP00000001090 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.925 |
| ADSS2 | GOT2 | ENSOARP00000005975 | ENSOARP00000001804 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.928 |
| ADSS2 | NAT8L | ENSOARP00000005975 | ENSOARP00000016720 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | N-acetyltransferase domain-containing protein. | 0.900 |