W5P3M1_SHEEP protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

W5P3M1_SHEEP

FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (70 aa)

Predicted Functional Partners:

FXYD5

0.769

FXYD7

0.719

FXYD2

0.714

FXYD6

0.651

TMEM63A

0.613

ATP1B3

0.486

ATP1B1

0.435

HSD11B2

0.418

SCNN1A

0.416

CEBPG

0.410

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B1	ATP1B3	ENSOARP00000010054	ENSOARP00000006955	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.951
ATP1B1	FXYD2	ENSOARP00000010054	ENSOARP00000007530	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	0.999
ATP1B1	FXYD6	ENSOARP00000010054	ENSOARP00000007569	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.877
ATP1B1	FXYD7	ENSOARP00000010054	ENSOARP00000005048	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.467
ATP1B1	W5P3M1_SHEEP	ENSOARP00000010054	ENSOARP00000005023	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.435
ATP1B3	ATP1B1	ENSOARP00000006955	ENSOARP00000010054	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	0.951
ATP1B3	FXYD2	ENSOARP00000006955	ENSOARP00000007530	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	0.978
ATP1B3	FXYD6	ENSOARP00000006955	ENSOARP00000007569	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.753
ATP1B3	W5P3M1_SHEEP	ENSOARP00000006955	ENSOARP00000005023	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.486
CEBPG	W5P3M1_SHEEP	ENSOARP00000011982	ENSOARP00000005023	CCAAT enhancer binding protein gamma.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.410
FXYD2	ATP1B1	ENSOARP00000007530	ENSOARP00000010054	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	0.999
FXYD2	ATP1B3	ENSOARP00000007530	ENSOARP00000006955	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.978
FXYD2	FXYD5	ENSOARP00000007530	ENSOARP00000005054	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.755
FXYD2	FXYD7	ENSOARP00000007530	ENSOARP00000005048	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.639
FXYD2	W5P3M1_SHEEP	ENSOARP00000007530	ENSOARP00000005023	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.714
FXYD5	FXYD2	ENSOARP00000005054	ENSOARP00000007530	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.	0.755
FXYD5	FXYD6	ENSOARP00000005054	ENSOARP00000007569	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.635
FXYD5	FXYD7	ENSOARP00000005054	ENSOARP00000005048	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.699
FXYD5	W5P3M1_SHEEP	ENSOARP00000005054	ENSOARP00000005023	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.769
FXYD6	ATP1B1	ENSOARP00000007569	ENSOARP00000010054	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.	0.877