STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (479 aa)    
Predicted Functional Partners:
ENOX1
Ecto-NOX disulfide-thiol exchanger 1.
      
 0.745
VPS28
VPS28 subunit of ESCRT-I; Belongs to the VPS28 family.
    
 
 0.742
VWA3B
Von Willebrand factor A domain containing 3B.
      
 0.695
ARF6
ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.628
TSG101
Tumor susceptibility 101.
    
 
 0.624
NEDD4
E3 ubiquitin-protein ligase.
   
 
 0.619
TET2
Tet methylcytosine dioxygenase 2.
      
 0.618
ARF1
ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.608
GAPVD1
GTPase activating protein and VPS9 domains 1.
   
 
 0.602
RABGEF1
Uncharacterized protein.
   
 
 0.583
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.