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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKUB1Ankyrin repeat and ubiquitin domain containing 1. (544 aa)    
Predicted Functional Partners:
LRRC71
Leucine rich repeat containing 71.
      
 0.536
TCTEX1D1
Tctex1 domain containing 1.
      
 0.536
ANKRD66
Ankyrin repeat domain 66.
      
0.536
TMEM255A
Transmembrane protein 255A.
      
 0.536
FAM216B
Family with sequence similarity 216 member B.
      
 0.530
DAW1
Dynein assembly factor with WD repeats 1.
      
 0.524
PPP1R17
Protein phosphatase 1 regulatory subunit 17.
      
 0.520
MAP3K19
Mitogen-activated protein kinase kinase kinase 19.
   
  
 0.516
CCDC114
Uncharacterized protein.
      
 0.516
COMMD2
COMM domain containing 2.
      
 0.483
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.