STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR45BUncharacterized protein. (329 aa)    
Predicted Functional Partners:
WIPI1
Uncharacterized protein.
   
 0.855
SGSM2
Small G protein signaling modulator 2.
      
 0.835
PEX1
Peroxisomal biogenesis factor 1.
    
 
 0.822
PCDH19
Protocadherin 19.
      
 0.727
SNCG
Gamma-synuclein; Belongs to the synuclein family.
      
 0.684
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.669
C16orf70
Chromosome 16 open reading frame 70.
   
  
 0.624
ZFYVE1
Zinc finger FYVE-type containing 1.
    
 
 0.552
W5Q502_SHEEP
Uncharacterized protein.
   
  
 0.552
BCAS3
BCAS3 microtubule associated cell migration factor.
   
  
 0.552
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.