STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (523 aa)    
Predicted Functional Partners:
GABRA2
Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 
 0.930
CDC42
Cell division cycle 42.
    
 0.905
ARHGEF39
Rho guanine nucleotide exchange factor 39.
    
 0.824
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
   
 
 0.817
GPHN
Gephyrin.
   
 
 0.729
ARHGEF19
Rho guanine nucleotide exchange factor 19.
   
 
 0.722
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
0.638
CHD1L
Chromodomain helicase DNA binding protein 1 like.
    
 
 0.635
FCRL3
Fc receptor like 3.
      
 0.626
NLGN2
Neuroligin 2.
   
  
 0.620
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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