STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTMR8Uncharacterized protein. (692 aa)    
Predicted Functional Partners:
SACM1L
SAC1 like phosphatidylinositide phosphatase.
     
 0.924
FIG4
FIG4 phosphoinositide 5-phosphatase.
   
 
 0.920
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
     
 0.917
INPP4A
Inositol polyphosphate-4-phosphatase type I A.
     
 0.909
INPP4B
Inositol polyphosphate-4-phosphatase type II B.
     
 0.906
INPP5F
Inositol polyphosphate-5-phosphatase F.
     
 0.903
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.903
PIP4P2
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
     
  0.900
PIP4P1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
     
  0.900
ZC3H12B
Zinc finger CCCH-type containing 12B.
      
 0.823
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.