SDC2 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SDC2

Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)

Predicted Functional Partners:

SDC1

0.969

SDC4

0.926

FN1

0.925

EZR

0.900

MSN

0.900

RDX

0.900

TRPC7

0.587

VTN

0.572

LDLRAD4

0.482

TRAPPC4

0.478

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EZR	MSN	ENSOARP00000002929	ENSOARP00000005414	FERM domain-containing protein.	Moesin.	0.991
EZR	RDX	ENSOARP00000002929	ENSOARP00000014242	FERM domain-containing protein.	Radixin.	0.995
EZR	SDC2	ENSOARP00000002929	ENSOARP00000005160	FERM domain-containing protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.900
FN1	LDLRAD4	ENSOARP00000020765	ENSOARP00000002262	Fibronectin 1.	Low density lipoprotein receptor class A domain containing 4.	0.457
FN1	SDC1	ENSOARP00000020765	ENSOARP00000018418	Fibronectin 1.	Uncharacterized protein.	0.904
FN1	SDC2	ENSOARP00000020765	ENSOARP00000005160	Fibronectin 1.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.925
FN1	SDC4	ENSOARP00000020765	ENSOARP00000005590	Fibronectin 1.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.940
FN1	VTN	ENSOARP00000020765	ENSOARP00000019327	Fibronectin 1.	SMB domain-containing protein.	0.640
LDLRAD4	FN1	ENSOARP00000002262	ENSOARP00000020765	Low density lipoprotein receptor class A domain containing 4.	Fibronectin 1.	0.457
LDLRAD4	SDC2	ENSOARP00000002262	ENSOARP00000005160	Low density lipoprotein receptor class A domain containing 4.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.482
MSN	EZR	ENSOARP00000005414	ENSOARP00000002929	Moesin.	FERM domain-containing protein.	0.991
MSN	RDX	ENSOARP00000005414	ENSOARP00000014242	Moesin.	Radixin.	0.997
MSN	SDC2	ENSOARP00000005414	ENSOARP00000005160	Moesin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.900
RDX	EZR	ENSOARP00000014242	ENSOARP00000002929	Radixin.	FERM domain-containing protein.	0.995
RDX	MSN	ENSOARP00000014242	ENSOARP00000005414	Radixin.	Moesin.	0.997
RDX	SDC2	ENSOARP00000014242	ENSOARP00000005160	Radixin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.900
SDC1	FN1	ENSOARP00000018418	ENSOARP00000020765	Uncharacterized protein.	Fibronectin 1.	0.904
SDC1	SDC2	ENSOARP00000018418	ENSOARP00000005160	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.969
SDC1	SDC4	ENSOARP00000018418	ENSOARP00000005590	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.979
SDC1	TRAPPC4	ENSOARP00000018418	ENSOARP00000013413	Uncharacterized protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.592