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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF28Rho guanine nucleotide exchange factor 28. (1654 aa)    
Predicted Functional Partners:
RHOA
RHOA.
   
 0.985
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.966
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.954
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
0.932
GNAQ
G protein subunit alpha q.
    
 0.904
W5Q4M2_SHEEP
Uncharacterized protein.
   
 0.857
NOL8
Nucleolar protein 8.
      
 0.850
RHOB
Uncharacterized protein.
   
 0.846
SBNO2
Strawberry notch homolog 2.
   
  
 0.677
ZDHHC23
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.662
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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