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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PI3WAP domain-containing protein. (160 aa)    
Predicted Functional Partners:
HELLS
Helicase, lymphoid specific.
      
 0.654
OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
      
 0.624
ABCF2
Uncharacterized protein.
      
 0.583
SH3YL1
SH3 and SYLF domain containing 1.
      
 0.532
KLK10
Kallikrein related peptidase 10; Belongs to the peptidase S1 family.
      
 0.520
LCN2
Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.519
CSTA
Cystatin A; Belongs to the cystatin family.
    
 0.504
RAB34
RAB34, member RAS oncogene family.
      
 0.489
GCAT
Glycine C-acetyltransferase.
      
 0.480
VPS36
Vacuolar protein sorting 36 homolog.
      
 0.477
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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