STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEA1Uncharacterized protein. (191 aa)    
Predicted Functional Partners:
KLC4
Kinesin light chain 4.
      
 0.837
CUL7
Cullin 7; Belongs to the cullin family.
   
  
 0.794
NDUFS7
NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family.
   
    0.769
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
      
 0.751
KLHDC3
Kelch domain containing 3.
      
 0.568
PHKG2
PHKG2; Belongs to the protein kinase superfamily.
      
 0.538
SFI1
SFI1 centrin binding protein.
      
 0.537
SPZ1
Spermatogenic leucine zipper 1.
      
 0.535
ZMYND10
Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.
      
 0.535
MC4R
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.485
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.