Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1289 aa)    
Predicted Functional Partners:
FIG4
FIG4 phosphoinositide 5-phosphatase.
      
 0.905
LITAF
Lipopolysaccharide induced TNF factor.
   
  
 0.867
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
      
 0.864
MPZ
Myelin protein zero.
      
 0.847
AP5S1
Adaptor related protein complex 5 subunit sigma 1.
      
 0.815
ZNF367
Zinc finger protein 367.
      
 0.765
MTMR2
Myotubularin related protein 2.
      
 0.748
ZBTB3
Zinc finger and BTB domain containing 3.
      
 0.746
IGHMBP2
Immunoglobulin mu DNA binding protein 2.
      
 0.720
ARFGAP2
ADP ribosylation factor GTPase activating protein 2.
      
 0.719
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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