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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRPT1tRNA phosphotransferase 1. (254 aa)    
Predicted Functional Partners:
THYN1
Thymocyte nuclear protein 1.
      
 0.918
VKORC1
Vitamin K epoxide reductase complex subunit 1.
   
  
 0.876
NUDT22
Nudix hydrolase 22.
 
 
  
 0.788
NRL
Neural retina leucine zipper.
   
  
 0.787
XPOT
Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.
   
  
 0.709
PARP10
Poly [ADP-ribose] polymerase.
  
  
 0.708
TARS2
Threonyl-tRNA synthetase 2, mitochondrial.
     
 0.664
PUSL1
tRNA pseudouridine synthase.
     
 0.618
TFPT
TCF3 fusion partner.
      
 0.590
W5P9H5_SHEEP
Poly [ADP-ribose] polymerase.
   
  
 0.577
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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