W5P4H9_SHEEP protein (Ovis aries) - STRING interaction network

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Score

W5P4H9_SHEEP

Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (392 aa)

Predicted Functional Partners:

CTSB

0.788

W5P0G0_SHEEP

0.783

AGT

0.731

ATP6AP2

0.722

LAMP1

0.704

W5QB18_SHEEP

0.704

IDE

0.681

LAMP2

0.647

EEA1

0.630

TFEB

0.579

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	ATP6AP2	ENSOARP00000003247	ENSOARP00000001383	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	ATPase H+ transporting accessory protein 2.	0.932
AGT	CTSB	ENSOARP00000003247	ENSOARP00000016378	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	0.622
AGT	W5P4H9_SHEEP	ENSOARP00000003247	ENSOARP00000005332	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.731
ATP6AP2	AGT	ENSOARP00000001383	ENSOARP00000003247	ATPase H+ transporting accessory protein 2.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	0.932
ATP6AP2	W5P4H9_SHEEP	ENSOARP00000001383	ENSOARP00000005332	ATPase H+ transporting accessory protein 2.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.722
CTSB	AGT	ENSOARP00000016378	ENSOARP00000003247	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	0.622
CTSB	EEA1	ENSOARP00000016378	ENSOARP00000016984	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Early endosome antigen 1.	0.668
CTSB	LAMP1	ENSOARP00000016378	ENSOARP00000008813	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Lysosomal associated membrane protein 1.	0.886
CTSB	LAMP2	ENSOARP00000016378	ENSOARP00000014124	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Lysosomal associated membrane protein 2.	0.746
CTSB	TFEB	ENSOARP00000016378	ENSOARP00000002461	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Transcription factor EB.	0.723
CTSB	W5P4H9_SHEEP	ENSOARP00000016378	ENSOARP00000005332	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.788
CTSB	W5QB18_SHEEP	ENSOARP00000016378	ENSOARP00000019913	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	Uncharacterized protein.	0.680
EEA1	CTSB	ENSOARP00000016984	ENSOARP00000016378	Early endosome antigen 1.	Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.	0.668
EEA1	LAMP1	ENSOARP00000016984	ENSOARP00000008813	Early endosome antigen 1.	Lysosomal associated membrane protein 1.	0.967
EEA1	LAMP2	ENSOARP00000016984	ENSOARP00000014124	Early endosome antigen 1.	Lysosomal associated membrane protein 2.	0.962
EEA1	W5P0G0_SHEEP	ENSOARP00000016984	ENSOARP00000003908	Early endosome antigen 1.	Uncharacterized protein.	0.483
EEA1	W5P4H9_SHEEP	ENSOARP00000016984	ENSOARP00000005332	Early endosome antigen 1.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.630
EEA1	W5QB18_SHEEP	ENSOARP00000016984	ENSOARP00000019913	Early endosome antigen 1.	Uncharacterized protein.	0.692
IDE	W5P0G0_SHEEP	ENSOARP00000000325	ENSOARP00000003908	Insulin degrading enzyme; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.982
IDE	W5P4H9_SHEEP	ENSOARP00000000325	ENSOARP00000005332	Insulin degrading enzyme; Belongs to the peptidase M16 family.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.681