STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3BGRL3Glutaredoxin domain-containing protein. (178 aa)    
Predicted Functional Partners:
TBCK
TBC1 domain containing kinase.
      
 0.832
BRWD3
Bromodomain and WD repeat domain containing 3.
      
 0.825
UBE2F
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.820
SVIL
Supervillin.
    
 
 0.662
PLXNB2
Plexin B2.
      
 0.625
PLXNB2-2
PSI domain-containing protein.
      
 0.609
AUTS2
Uncharacterized protein.
      
 0.578
TXNDC11
Thioredoxin domain containing 11.
      
 0.538
HEPACAM2
HEPACAM family member 2.
      
 0.506
RCN1
Uncharacterized protein.
   
  
 0.499
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.