STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFITM10Interferon induced transmembrane protein 10. (176 aa)    
Predicted Functional Partners:
IFITM5
Interferon induced transmembrane protein 5.
      
 0.937
W5QF86_SHEEP
Uncharacterized protein.
      
 0.649
ZBTB7A
Zinc finger and BTB domain containing 7A.
    
 
 0.597
VAPA
VAMP associated protein A.
    
 
 0.595
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.539
GLDN
Gliomedin.
      
 0.538
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.516
IL31RA
Interleukin 31 receptor A.
   
 
 0.502
CTSB
Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). Belongs to the peptidase C1 family.
   
 0.492
ESRRG
Estrogen related receptor gamma.
      
 0.478
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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