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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM219Transmembrane protein 219. (239 aa)    
Predicted Functional Partners:
IGFBP3
Thyroglobulin type-1 domain-containing protein.
    
 0.931
CDC20B
Cell division cycle 20B.
   
 
  0.629
CDC20
Cell division cycle 20.
   
 
  0.629
W5P637_SHEEP
Uncharacterized protein.
      
 0.612
KCTD13
Potassium channel tetramerization domain containing 13.
      
 0.536
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
  
 0.493
GPATCH4
G-patch domain containing 4.
      
 0.483
QPRT
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
      
 0.482
ASPHD1
Aspartate beta-hydroxylase domain containing 1.
      
 0.476
INO80E
INO80 complex subunit E.
   
  
 0.470
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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