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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (351 aa)    
Predicted Functional Partners:
NOTCH2
Notch receptor 2.
    
 0.797
POFUT1
Protein O-fucosyltransferase 1.
      
 0.764
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.738
DTX3
Deltex E3 ubiquitin ligase 3.
      
 0.736
W5NSK3_SHEEP
Uncharacterized protein.
   
 0.654
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.653
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.642
POGLUT1
Protein O-glucosyltransferase 1.
      
 0.634
W5P4X8_SHEEP
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.569
POLR2H
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.562
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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