STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GJD4Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (367 aa)    
Predicted Functional Partners:
W5NT56_SHEEP
CNX domain-containing protein.
     
 0.742
CIART
Circadian associated repressor of transcription.
      
 0.660
TAGAP
T cell activation RhoGTPase activating protein.
   
  
 0.632
SLC26A10
Solute carrier family 26 member 10.
      
 0.625
FAM78A
Family with sequence similarity 78 member A.
      
 0.623
PHYHIP
Phytanoyl-CoA 2-hydroxylase interacting protein.
      
 0.622
LIMS2
LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
      
 0.609
PLCL1
Phosphoinositide phospholipase C.
      
 0.597
RASL11A
RAS like family 11 member A.
   
  
 0.596
RTN4RL2
Uncharacterized protein.
      
 0.583
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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