PHF12 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4A	ARID4B	ENSOARP00000022686	ENSOARP00000003717	AT-rich interaction domain 4A.	AT-rich interaction domain 4B.	0.666
ARID4A	EMSY	ENSOARP00000022686	ENSOARP00000013783	AT-rich interaction domain 4A.	EMSY transcriptional repressor, BRCA2 interacting.	0.498
ARID4A	GATAD1	ENSOARP00000022686	ENSOARP00000019516	AT-rich interaction domain 4A.	GATA zinc finger domain containing 1.	0.555
ARID4A	HDAC1	ENSOARP00000022686	ENSOARP00000022517	AT-rich interaction domain 4A.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.817
ARID4A	HDAC2	ENSOARP00000022686	ENSOARP00000010190	AT-rich interaction domain 4A.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.817
ARID4A	PHF12	ENSOARP00000022686	ENSOARP00000005385	AT-rich interaction domain 4A.	PHD finger protein 12.	0.840
ARID4A	SETD2	ENSOARP00000022686	ENSOARP00000005431	AT-rich interaction domain 4A.	SET domain containing 2, histone lysine methyltransferase.	0.424
ARID4A	SIN3A	ENSOARP00000022686	ENSOARP00000002349	AT-rich interaction domain 4A.	SIN3 transcription regulator family member A.	0.849
ARID4A	SIN3B	ENSOARP00000022686	ENSOARP00000019867	AT-rich interaction domain 4A.	SIN3 transcription regulator family member B.	0.849
ARID4B	ARID4A	ENSOARP00000003717	ENSOARP00000022686	AT-rich interaction domain 4B.	AT-rich interaction domain 4A.	0.666
ARID4B	EMSY	ENSOARP00000003717	ENSOARP00000013783	AT-rich interaction domain 4B.	EMSY transcriptional repressor, BRCA2 interacting.	0.545
ARID4B	GATAD1	ENSOARP00000003717	ENSOARP00000019516	AT-rich interaction domain 4B.	GATA zinc finger domain containing 1.	0.555
ARID4B	HDAC1	ENSOARP00000003717	ENSOARP00000022517	AT-rich interaction domain 4B.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.858
ARID4B	HDAC2	ENSOARP00000003717	ENSOARP00000010190	AT-rich interaction domain 4B.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.854
ARID4B	PHF12	ENSOARP00000003717	ENSOARP00000005385	AT-rich interaction domain 4B.	PHD finger protein 12.	0.827
ARID4B	SETD2	ENSOARP00000003717	ENSOARP00000005431	AT-rich interaction domain 4B.	SET domain containing 2, histone lysine methyltransferase.	0.494
ARID4B	SIN3A	ENSOARP00000003717	ENSOARP00000002349	AT-rich interaction domain 4B.	SIN3 transcription regulator family member A.	0.906
ARID4B	SIN3B	ENSOARP00000003717	ENSOARP00000019867	AT-rich interaction domain 4B.	SIN3 transcription regulator family member B.	0.842
BTAF1	PHF12	ENSOARP00000017755	ENSOARP00000005385	B-TFIID TATA-box binding protein associated factor 1.	PHD finger protein 12.	0.815
EMSY	ARID4A	ENSOARP00000013783	ENSOARP00000022686	EMSY transcriptional repressor, BRCA2 interacting.	AT-rich interaction domain 4A.	0.498