STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHF12PHD finger protein 12. (1004 aa)    
Predicted Functional Partners:
W5NUN9_SHEEP
MRG domain-containing protein.
    
 0.973
W5PYR2_SHEEP
MRG domain-containing protein.
    
 0.973
MORF4L1
Mortality factor 4 like 1.
    
 0.973
SIN3A
SIN3 transcription regulator family member A.
   
 0.928
GATAD1
GATA zinc finger domain containing 1.
    
 
 0.917
SIN3B
SIN3 transcription regulator family member B.
   
 
 0.896
ARID4B
AT-rich interaction domain 4B.
    
 
 0.866
EMSY
EMSY transcriptional repressor, BRCA2 interacting.
   
 
 0.859
ARID4A
AT-rich interaction domain 4A.
    
 
 0.845
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.792
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.