STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUFY2RUN and FYVE domain containing 2. (614 aa)    
Predicted Functional Partners:
RAB33A
RAB33A, member RAS oncogene family.
    
 
 0.629
HOOK1
Hook microtubule tethering protein 1.
      
 0.580
ARL8B
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.550
FRMD4A
FERM domain containing 4A.
      
 0.521
HMCN1
Hemicentin 1.
      
 0.520
CLIP1
CAP-Gly domain containing linker protein 1.
   
 
 0.518
ERC1
ELKS/RAB6-interacting/CAST family member 1.
      
 0.516
HOXD9
Homeobox domain-containing protein.
      
 0.483
CCDC6
Coiled-coil domain containing 6.
      
 0.482
SCNN1A
Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.482
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.