STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD2SET domain containing 2, histone lysine methyltransferase. (2556 aa)    
Predicted Functional Partners:
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
 
 0.886
W5PS91_SHEEP
Histone H3; Belongs to the histone H3 family.
   
 0.879
LOC101115753
Histone H3; Belongs to the histone H3 family.
   
 0.879
ASH1L
ASH1 like histone lysine methyltransferase.
   
  
0.874
H3-4
Histone H3; Belongs to the histone H3 family.
   
 0.872
POLR2C
RNA polymerase II subunit C.
   
 0.859
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.854
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.844
NIPBL
Nipped-B protein.
   
  
 0.842
SON
SON DNA binding protein.
   
 0.835
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.