PRODH2 protein (Ovis aries) - STRING interaction network

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PRODH2

Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (469 aa)

Predicted Functional Partners:

PYCR3

0.949

PYCR2

0.929

OAT

0.928

PYCR1

0.926

P4HA1

0.909

P4HA3

0.909

P4HA2

0.909

COX2

0.855

COX3

0.848

COX1

0.839

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COX1	COX2	ENSOARP00000000003	ENSOARP00000000004	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.999
COX1	COX3	ENSOARP00000000003	ENSOARP00000000007	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.999
COX1	PRODH2	ENSOARP00000000003	ENSOARP00000005448	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.839
COX2	COX1	ENSOARP00000000004	ENSOARP00000000003	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.999
COX2	COX3	ENSOARP00000000004	ENSOARP00000000007	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.999
COX2	PRODH2	ENSOARP00000000004	ENSOARP00000005448	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.855
COX3	COX1	ENSOARP00000000007	ENSOARP00000000003	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.999
COX3	COX2	ENSOARP00000000007	ENSOARP00000000004	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	0.999
COX3	PRODH2	ENSOARP00000000007	ENSOARP00000005448	Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.848
OAT	PRODH2	ENSOARP00000010783	ENSOARP00000005448	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.928
OAT	PYCR1	ENSOARP00000010783	ENSOARP00000019053	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.582
OAT	PYCR2	ENSOARP00000010783	ENSOARP00000019071	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.599
OAT	PYCR3	ENSOARP00000010783	ENSOARP00000017937	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.691
P4HA1	P4HA2	ENSOARP00000007878	ENSOARP00000016515	Prolyl 4-hydroxylase subunit alpha 1.	Prolyl 4-hydroxylase subunit alpha 2.	0.940
P4HA1	P4HA3	ENSOARP00000007878	ENSOARP00000010387	Prolyl 4-hydroxylase subunit alpha 1.	Prolyl 4-hydroxylase subunit alpha 3.	0.910
P4HA1	PRODH2	ENSOARP00000007878	ENSOARP00000005448	Prolyl 4-hydroxylase subunit alpha 1.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.909
P4HA1	PYCR1	ENSOARP00000007878	ENSOARP00000019053	Prolyl 4-hydroxylase subunit alpha 1.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.900
P4HA1	PYCR2	ENSOARP00000007878	ENSOARP00000019071	Prolyl 4-hydroxylase subunit alpha 1.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.900
P4HA1	PYCR3	ENSOARP00000007878	ENSOARP00000017937	Prolyl 4-hydroxylase subunit alpha 1.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.902
P4HA2	P4HA1	ENSOARP00000016515	ENSOARP00000007878	Prolyl 4-hydroxylase subunit alpha 2.	Prolyl 4-hydroxylase subunit alpha 1.	0.940