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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM72AUncharacterized protein. (150 aa)    
Predicted Functional Partners:
ARHGAP11A
Rho GTPase activating protein 11A.
   
  
 0.902
PTPN20
Protein tyrosine phosphatase non-receptor type 20.
      
 0.876
ARHGEF5
Rho guanine nucleotide exchange factor 5.
      
 0.876
BOLA2B
Uncharacterized protein; Belongs to the BolA/IbaG family.
      
 0.780
CBWD1
Uncharacterized protein.
      
 0.712
DLGAP5
DLG associated protein 5.
   
    0.676
TTK
TTK protein kinase.
   
  
 0.673
NDC80
NDC80 kinetochore complex component.
   
    0.673
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
    0.673
KIF2C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
    0.669
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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