STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (634 aa)    
Predicted Functional Partners:
CSRNP1
Cysteine and serine rich nuclear protein 1.
      
 0.745
ANKRD22
Ankyrin repeat domain 22.
    
 
 0.727
APBB1
Amyloid beta precursor protein binding family B member 1.
      
 0.696
TP53BP2
Tumor protein p53 binding protein 2.
   
  
 0.688
CLEC12A
C-type lectin domain-containing protein.
   
 0.678
ARID5A
AT-rich interaction domain 5A.
      
 0.673
AMPD3
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
  
 0.664
NCR3
Natural cytotoxicity triggering receptor 3.
      
 0.644
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
   
  
 0.627
TCN1
Transcobalamin 1.
      
 0.627
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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