STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK2AP1Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (121 aa)    
Predicted Functional Partners:
GATAD2A
GATA zinc finger domain containing 2A.
    
 
 0.956
CHD3
Chromodomain helicase DNA binding protein 3.
   
 
 0.856
GATAD2B
GATA zinc finger domain containing 2B.
    
 
 0.751
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 
 0.744
RBBP4
WD_REPEATS_REGION domain-containing protein.
   
 
 0.689
GADD45GIP1
GADD45G interacting protein 1.
      
 0.685
CABLES1
Cdk5 and Abl enzyme substrate 1.
      
 0.625
CHD4
Uncharacterized protein.
   
 
 0.619
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 
 0.617
W5NT16_SHEEP
Uncharacterized protein.
    
 
 0.602
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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