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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBPUncharacterized protein. (315 aa)    
Predicted Functional Partners:
GTF2B
General transcription factor IIB.
   
 0.995
TAF1
Transcription initiation factor TFIID subunit.
    
 0.976
TAF2
TATA-box binding protein associated factor 2.
    
 0.975
SP1
Sp1 transcription factor.
    
 0.967
TAF12
TATA-box binding protein associated factor 12.
    
 0.953
BRF1
BRF1 RNA polymerase III transcription initiation factor subunit.
   
 0.945
TAF6
TATA-box binding protein associated factor 6.
   
 0.944
TAF10
TATA-box binding protein associated factor 10.
    
 0.942
BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB.
    
 0.941
TAF9B
TATA-box binding protein associated factor 9b.
    
 0.939
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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