close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5P546_SHEEPLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (182 aa)    
Predicted Functional Partners:
LYZL6
Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.636
LALBA
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.634
ZNF613
Zinc finger protein 613.
    
 
 0.588
CSN3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
   
 
 0.569
RBP4
Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.
      
 0.483
CDC73
Cell division cycle 73.
   
 0.467
KRT4
Keratin 4; Belongs to the intermediate filament family.
    
 
 0.438
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.425
W5PZZ1_SHEEP
KRAB domain-containing protein.
    
 
 0.409
W5Q060_SHEEP
Uncharacterized protein.
    
 
 0.409
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (30%) [HD]