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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLG2Discs large MAGUK scaffold protein 2. (905 aa)    
Predicted Functional Partners:
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.915
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
  
 
0.911
DLG5
Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.
     
0.906
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
  
  
 
0.901
LLGL1
LLGL scribble cell polarity complex component 1.
   
 0.882
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
  
 
0.863
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
   
 0.803
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
0.794
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
    
 0.776
DLGAP1
DLG associated protein 1.
   
 0.726
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.