STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FECHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (423 aa)    
Predicted Functional Partners:
PPOX
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.976
W5Q2F3_SHEEP
Uncharacterized protein.
  
 
 0.976
UROD
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.956
FXN
Frataxin.
    
 
 0.901
CPOX
Uncharacterized protein.
     
 0.895
HEMK1
HemK methyltransferase family member 1.
    
 0.859
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
    
 0.859
ENDOV
Endonuclease V.
  
  
 0.857
UROS
Uroporphyrinogen III synthase.
  
  
 0.823
EPB42
Erythrocyte membrane protein band 4.2.
   
  
 0.788
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.