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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf65Chromosome 12 open reading frame 65. (169 aa)    
Predicted Functional Partners:
MRPL58
Mitochondrial ribosomal protein L58.
   
 
 0.847
HEMK1
HemK methyltransferase family member 1.
  
 
 0.776
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
  
 
 0.776
GFM2
Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
  
 
 0.746
MRPS18B
Mitochondrial ribosomal protein S18B.
   
 
 0.742
MRPL27
Mitochondrial ribosomal protein L27.
  
 
 0.726
MRPL20
Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.717
MRPL17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
  
 
 0.711
MRPL9
Mitochondrial ribosomal protein L9.
  
 
 0.708
MRPS16
Mitochondrial ribosomal protein S16.
  
 
 0.704
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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