close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL22Methyltransferase like 22. (387 aa)    
Predicted Functional Partners:
KIN
Kin17 DNA and RNA binding protein.
    
 0.965
METTL18
Methyltransferase like 18.
      
 0.843
METTL21A
Methyltransferase like 21A.
   
 
 0.776
CAMKMT
Calmodulin-lysine N-methyltransferase.
      
 0.769
SLC25A53
Solute carrier family 25 member 53; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.634
METTL21C
Methyltransferase like 21C.
   
 
 0.632
EEF2
Eukaryotic translation elongation factor 2.
    
 0.626
METTL23
Methyltransferase like 23.
   
 
 0.617
GRWD1
Glutamate rich WD repeat containing 1.
      
 0.613
B9D1
B9 domain containing 1.
    
 0.534
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.