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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (232 aa)    
Predicted Functional Partners:
TIMM44
Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.
   
 0.967
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
  
 0.964
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.893
COX5B
Cytochrome c oxidase subunit 5B.
   
 0.892
HSPA12A
Heat shock protein family A (Hsp70) member 12A.
  
 0.827
W5Q1T4_SHEEP
Uncharacterized protein; Belongs to the GroES chaperonin family.
  
 
 0.775
LOC106990104
HSP10; Belongs to the GroES chaperonin family.
  
 
 0.775
LOC101122667
10 kDa heat shock protein, mitochondrial.
  
 
 0.775
HSPA6
Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family.
  
 0.741
C1orf198
Chromosome 1 open reading frame 198.
   
 0.735
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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