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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAMD14Sterile alpha motif domain containing 14. (403 aa)    
Predicted Functional Partners:
PPP1R9B
Protein phosphatase 1 regulatory subunit 9B.
 
    
 0.989
BLOC1S1
Uncharacterized protein.
      
 0.696
SAMD5
Sterile alpha motif domain containing 5.
      
 0.578
KPRP
Keratinocyte proline rich protein.
      
 0.575
SAMD1
Sterile alpha motif domain containing 1.
      
 0.538
EXOSC8
Exosome component 8.
      
 0.538
SAMD7
Sterile alpha motif domain containing 7.
      
 0.534
MFSD2B
Major facilitator superfamily domain containing 2B.
      
 0.512
CRNN
Cornulin.
    
 
 0.501
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4.
      
 0.487
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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