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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIAA0040KIAA0040. (99 aa)    
Predicted Functional Partners:
ZBTB37
Zinc finger and BTB domain containing 37.
      
 0.670
SLC9C2
Solute carrier family 9 member C2 (putative).
      
 0.658
TEX50
Testis expressed 50.
      
 0.653
ANKRD45
ANK_REP_REGION domain-containing protein.
      
 0.624
SUCO
SUN domain containing ossification factor.
      
 0.612
ZNF319
Zinc finger protein 319.
      
 0.581
PIGC
Phosphatidylinositol glycan anchor biosynthesis class C.
      
 0.581
ZBTB24
Zinc finger and BTB domain containing 24.
      
 0.575
PRR15L
Proline rich 15 like.
      
 0.538
C1orf116
Chromosome 1 open reading frame 116.
      
 0.538
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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