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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRR7Proline rich 7, synaptic. (269 aa)    
Predicted Functional Partners:
LOC101115276
Olfactory receptor.
      
 0.928
LOC101116053
Olfactory receptor.
      
 0.928
FAF2
Fas associated factor family member 2.
      
 0.902
LOC101109615
Olfactory receptor.
      
 0.887
BTNL9
Butyrophilin like 9.
      
 0.875
LMAN2
Lectin, mannose binding 2.
      
 0.854
TRIM52
Tripartite motif containing 52.
      
 0.836
LOC101112979
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.823
LOC101107785
Olfactory receptor.
      
 0.823
W5PB35_SHEEP
Uncharacterized protein.
      
 0.821
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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