STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCC2Methylcrotonoyl-CoA carboxylase 2. (563 aa)    
Predicted Functional Partners:
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
 
 0.999
IVD
Isovaleryl-CoA dehydrogenase.
 
 
 0.982
PCCA
Propionyl-CoA carboxylase subunit alpha.
 
 0.962
ECHS1
Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.959
AUH
AU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.948
W5Q8A9_SHEEP
Acyl-CoA_dh_1 domain-containing protein.
  
 
 0.948
HADHA
Enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.947
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.
  
 0.946
NELFCD
Negative elongation factor complex member C/D.
  
 0.925
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.922
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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