STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CFIUncharacterized protein; Belongs to the peptidase S1 family. (618 aa)    
Predicted Functional Partners:
W5NRI1_SHEEP
A2M_N_2 domain-containing protein.
   
 0.971
W5PWS0_SHEEP
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
    
 0.958
W5PFF9_SHEEP
Uncharacterized protein.
   
 0.921
W5QAN8_SHEEP
Uncharacterized protein.
   
 0.921
LOC105611355
Uncharacterized protein.
    
 0.906
W5PX64_SHEEP
Uncharacterized protein.
    
 0.869
C2
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 
 0.858
MBLA
C-type lectin domain-containing protein.
   
 0.845
DGKE
Diacylglycerol kinase.
      
 0.829
CFP
Complement factor properdin.
   
 0.797
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.