HTR1A protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

HTR1A

G_PROTEIN_RECEP_F1_2 domain-containing protein. (422 aa)

Predicted Functional Partners:

GNG4

0.797

GNB4

0.795

GNB3

0.780

GNB1

0.774

GNAI2

0.771

GNAI1

0.771

GNAI3

0.771

NPY

0.753

GNGT2

0.752

GNG13

0.751

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAI1	GNAI2	ENSOARP00000018654	ENSOARP00000010904	G protein subunit alpha i1.	Uncharacterized protein.	0.934
GNAI1	GNAI3	ENSOARP00000018654	ENSOARP00000020673	G protein subunit alpha i1.	G protein subunit alpha i3.	0.933
GNAI1	GNB1	ENSOARP00000018654	ENSOARP00000001944	G protein subunit alpha i1.	G protein subunit beta 1.	0.896
GNAI1	GNB3	ENSOARP00000018654	ENSOARP00000006145	G protein subunit alpha i1.	G protein subunit beta 3.	0.907
GNAI1	GNB4	ENSOARP00000018654	ENSOARP00000022245	G protein subunit alpha i1.	G protein subunit beta 4.	0.993
GNAI1	GNG13	ENSOARP00000018654	ENSOARP00000015437	G protein subunit alpha i1.	G protein subunit gamma 13.	0.844
GNAI1	GNG4	ENSOARP00000018654	ENSOARP00000003750	G protein subunit alpha i1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.863
GNAI1	GNGT2	ENSOARP00000018654	ENSOARP00000006720	G protein subunit alpha i1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.849
GNAI1	HTR1A	ENSOARP00000018654	ENSOARP00000005711	G protein subunit alpha i1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.771
GNAI2	GNAI1	ENSOARP00000010904	ENSOARP00000018654	Uncharacterized protein.	G protein subunit alpha i1.	0.934
GNAI2	GNAI3	ENSOARP00000010904	ENSOARP00000020673	Uncharacterized protein.	G protein subunit alpha i3.	0.934
GNAI2	GNB1	ENSOARP00000010904	ENSOARP00000001944	Uncharacterized protein.	G protein subunit beta 1.	0.920
GNAI2	GNB3	ENSOARP00000010904	ENSOARP00000006145	Uncharacterized protein.	G protein subunit beta 3.	0.912
GNAI2	GNB4	ENSOARP00000010904	ENSOARP00000022245	Uncharacterized protein.	G protein subunit beta 4.	0.991
GNAI2	GNG13	ENSOARP00000010904	ENSOARP00000015437	Uncharacterized protein.	G protein subunit gamma 13.	0.844
GNAI2	GNG4	ENSOARP00000010904	ENSOARP00000003750	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.863
GNAI2	GNGT2	ENSOARP00000010904	ENSOARP00000006720	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.849
GNAI2	HTR1A	ENSOARP00000010904	ENSOARP00000005711	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.771
GNAI3	GNAI1	ENSOARP00000020673	ENSOARP00000018654	G protein subunit alpha i3.	G protein subunit alpha i1.	0.933
GNAI3	GNAI2	ENSOARP00000020673	ENSOARP00000010904	G protein subunit alpha i3.	Uncharacterized protein.	0.934