STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEZ6Seizure related 6 homolog. (959 aa)    
Predicted Functional Partners:
SDF2
Stromal cell derived factor 2.
    
 
 0.852
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
    
 0.821
SRR
Serine racemase.
   
 
 0.746
XAF1
XIAP associated factor 1.
    
 0.732
WSCD1
WSC domain containing 1.
   
 
 0.729
KARS1
Lysine--tRNA ligase.
    
 
 0.716
ATP2A3
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.659
RAMP2
Receptor activity modifying protein 2.
      
 0.625
PHF12
PHD finger protein 12.
    
 
 0.620
SHISAL2A
Shisa like 2A.
      
 0.613
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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