STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELFN1Uncharacterized protein. (205 aa)    
Predicted Functional Partners:
TRPM1
Transient receptor potential cation channel subfamily M member 1.
      
 0.948
W5P775_SHEEP
Uncharacterized protein.
   
 
 0.770
LRIT3
Leucine rich repeat, Ig-like and transmembrane domains 3.
    
0.757
CACNA2D4
Calcium voltage-gated channel auxiliary subunit alpha2delta 4.
   
 
 0.748
FAM155A
Uncharacterized protein.
    
 
 0.718
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.689
CTBP2
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.687
RGS11
Regulator of G protein signaling 11.
   
 
 0.673
CACNA1F
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 0.668
RGS7
Regulator of G protein signaling 7.
   
 
 0.665
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.