RCVRN protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RCVRN

Recoverin. (202 aa)

Predicted Functional Partners:

GRK1

0.999

W5PF50_SHEEP

0.996

RHO

0.993

GRK7

0.981

CRX

0.948

CALB1

0.910

PAX6

0.892

VSX2

0.887

NR2E3

0.877

OTX2

0.864

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALB1	CRX	ENSOARP00000011084	ENSOARP00000012286	Calbindin 1.	Cone-rod homeobox.	0.467
CALB1	OTX2	ENSOARP00000011084	ENSOARP00000022676	Calbindin 1.	Orthodenticle homeobox 2.	0.524
CALB1	PAX6	ENSOARP00000011084	ENSOARP00000017386	Calbindin 1.	Paired box 6.	0.895
CALB1	RCVRN	ENSOARP00000011084	ENSOARP00000005781	Calbindin 1.	Recoverin.	0.910
CALB1	RHO	ENSOARP00000011084	ENSOARP00000015330	Calbindin 1.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.693
CRX	CALB1	ENSOARP00000012286	ENSOARP00000011084	Cone-rod homeobox.	Calbindin 1.	0.467
CRX	GRK1	ENSOARP00000012286	ENSOARP00000002424	Cone-rod homeobox.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.429
CRX	NR2E3	ENSOARP00000012286	ENSOARP00000020205	Cone-rod homeobox.	Nuclear receptor subfamily 2 group E member 3.	0.958
CRX	RCVRN	ENSOARP00000012286	ENSOARP00000005781	Cone-rod homeobox.	Recoverin.	0.948
CRX	RHO	ENSOARP00000012286	ENSOARP00000015330	Cone-rod homeobox.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.945
GRK1	CRX	ENSOARP00000002424	ENSOARP00000012286	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Cone-rod homeobox.	0.429
GRK1	GRK7	ENSOARP00000002424	ENSOARP00000006995	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.901
GRK1	RCVRN	ENSOARP00000002424	ENSOARP00000005781	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Recoverin.	0.999
GRK1	RHO	ENSOARP00000002424	ENSOARP00000015330	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.999
GRK7	GRK1	ENSOARP00000006995	ENSOARP00000002424	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.901
GRK7	NR2E3	ENSOARP00000006995	ENSOARP00000020205	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Nuclear receptor subfamily 2 group E member 3.	0.564
GRK7	RCVRN	ENSOARP00000006995	ENSOARP00000005781	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Recoverin.	0.981
GRK7	RHO	ENSOARP00000006995	ENSOARP00000015330	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).	0.995
NR2E3	CRX	ENSOARP00000020205	ENSOARP00000012286	Nuclear receptor subfamily 2 group E member 3.	Cone-rod homeobox.	0.958
NR2E3	GRK7	ENSOARP00000020205	ENSOARP00000006995	Nuclear receptor subfamily 2 group E member 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.564