OS9 protein (Ovis aries) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OS9

OS9 endoplasmic reticulum lectin. (668 aa)

Predicted Functional Partners:

SYVN1

0.987

SEL1L

0.983

DERL2

0.980

DERL1

0.973

AMFR

0.922

VCP

0.897

HSP90B1

0.860

EDEM3

0.840

RNF139

0.829

SEL1L2

0.820

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSOARP00000019826	ENSOARP00000011741	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.995
AMFR	DERL2	ENSOARP00000019826	ENSOARP00000003322	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.963
AMFR	OS9	ENSOARP00000019826	ENSOARP00000005994	Autocrine motility factor receptor.	OS9 endoplasmic reticulum lectin.	0.922
AMFR	RNF139	ENSOARP00000019826	ENSOARP00000009735	Autocrine motility factor receptor.	Ring finger protein 139.	0.473
AMFR	SEL1L	ENSOARP00000019826	ENSOARP00000003196	Autocrine motility factor receptor.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.923
AMFR	SEL1L2	ENSOARP00000019826	ENSOARP00000012292	Autocrine motility factor receptor.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.751
AMFR	SYVN1	ENSOARP00000019826	ENSOARP00000013874	Autocrine motility factor receptor.	Synoviolin 1.	0.706
AMFR	VCP	ENSOARP00000019826	ENSOARP00000013073	Autocrine motility factor receptor.	Valosin containing protein; Belongs to the AAA ATPase family.	0.960
DERL1	AMFR	ENSOARP00000011741	ENSOARP00000019826	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.995
DERL1	DERL2	ENSOARP00000011741	ENSOARP00000003322	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.994
DERL1	EDEM3	ENSOARP00000011741	ENSOARP00000002962	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.494
DERL1	HSP90B1	ENSOARP00000011741	ENSOARP00000017581	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Heat shock protein 90 beta family member 1.	0.532
DERL1	OS9	ENSOARP00000011741	ENSOARP00000005994	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.973
DERL1	RNF139	ENSOARP00000011741	ENSOARP00000009735	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 139.	0.882
DERL1	SEL1L	ENSOARP00000011741	ENSOARP00000003196	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.981
DERL1	SEL1L2	ENSOARP00000011741	ENSOARP00000012292	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.917
DERL1	SYVN1	ENSOARP00000011741	ENSOARP00000013874	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Synoviolin 1.	0.984
DERL1	VCP	ENSOARP00000011741	ENSOARP00000013073	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.988
DERL2	AMFR	ENSOARP00000003322	ENSOARP00000019826	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.963
DERL2	DERL1	ENSOARP00000003322	ENSOARP00000011741	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.994