STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND1CDENN domain containing 1C. (801 aa)    
Predicted Functional Partners:
RAB35
RAB35, member RAS oncogene family.
    
 0.932
DENND4B
DENN domain containing 4B.
    
 
 0.899
DENND3
DENN domain containing 3.
    
 
 0.886
RAB28
RAS oncogene family 28 protein.
     
 0.874
RAB17
RAB17, member RAS oncogene family.
      
 0.849
RAB22A
RAB22A, member RAS oncogene family.
      
 0.801
RAB21
Uncharacterized protein.
      
 0.794
DENND5B
DENN domain containing 5B.
    
 
0.780
RAB13
Uncharacterized protein.
     
 0.721
AVL9
AVL9 cell migration associated.
      
 0.702
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.