STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED3Sprouty related EVH1 domain containing 3. (331 aa)    
Predicted Functional Partners:
NF1
Neurofibromin 1.
    
 0.825
NEK2
NIMA related kinase 2.
    
 0.617
RASA1
RAS p21 protein activator 1.
     
 0.444
ERAS
ES cell expressed Ras.
   
 0.434
HRAS
HRas proto-oncogene, GTPase.
   
 0.434
RALB
RAS like proto-oncogene B.
   
 0.434
RALA
RAS like proto-oncogene A.
   
 0.434
KRAS
KRAS proto-oncogene, GTPase.
   
 0.434
NRAS
NRAS proto-oncogene, GTPase.
   
 0.434
CSDE1
Cold shock domain containing E1.
   
 0.434
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.