GLG1 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GLG1

Golgi glycoprotein 1. (957 aa)

Predicted Functional Partners:

SELE

0.960

CCDC88A

0.780

C17orf75

0.737

FADD

0.693

FAM91A1

0.691

RFWD3

0.629

BTG3

0.624

WDR59

0.620

CASP8

0.618

DSC1

0.577

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTG3	GLG1	ENSOARP00000016950	ENSOARP00000006158	B cell translocation protein 3.	Golgi glycoprotein 1.	0.624
C17orf75	FAM91A1	ENSOARP00000011538	ENSOARP00000010341	Chromosome 17 open reading frame 75.	Family with sequence similarity 91 member A1.	0.930
C17orf75	GLG1	ENSOARP00000011538	ENSOARP00000006158	Chromosome 17 open reading frame 75.	Golgi glycoprotein 1.	0.737
CASP8	FADD	ENSOARP00000018175	ENSOARP00000019828	Caspase 8; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.999
CASP8	GLG1	ENSOARP00000018175	ENSOARP00000006158	Caspase 8; Belongs to the peptidase C14A family.	Golgi glycoprotein 1.	0.618
CASP8	RFWD3	ENSOARP00000018175	ENSOARP00000006442	Caspase 8; Belongs to the peptidase C14A family.	Ring finger and WD repeat domain 3.	0.506
CASP8	WDR59	ENSOARP00000018175	ENSOARP00000006780	Caspase 8; Belongs to the peptidase C14A family.	WD repeat domain 59.	0.506
CCDC88A	GLG1	ENSOARP00000002557	ENSOARP00000006158	Coiled-coil domain containing 88A.	Golgi glycoprotein 1.	0.780
DSC1	GLG1	ENSOARP00000007216	ENSOARP00000006158	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Golgi glycoprotein 1.	0.577
FADD	CASP8	ENSOARP00000019828	ENSOARP00000018175	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Caspase 8; Belongs to the peptidase C14A family.	0.999
FADD	GLG1	ENSOARP00000019828	ENSOARP00000006158	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Golgi glycoprotein 1.	0.693
FADD	RFWD3	ENSOARP00000019828	ENSOARP00000006442	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Ring finger and WD repeat domain 3.	0.533
FADD	WDR59	ENSOARP00000019828	ENSOARP00000006780	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	WD repeat domain 59.	0.550
FAM91A1	C17orf75	ENSOARP00000010341	ENSOARP00000011538	Family with sequence similarity 91 member A1.	Chromosome 17 open reading frame 75.	0.930
FAM91A1	GLG1	ENSOARP00000010341	ENSOARP00000006158	Family with sequence similarity 91 member A1.	Golgi glycoprotein 1.	0.691
GLG1	BTG3	ENSOARP00000006158	ENSOARP00000016950	Golgi glycoprotein 1.	B cell translocation protein 3.	0.624
GLG1	C17orf75	ENSOARP00000006158	ENSOARP00000011538	Golgi glycoprotein 1.	Chromosome 17 open reading frame 75.	0.737
GLG1	CASP8	ENSOARP00000006158	ENSOARP00000018175	Golgi glycoprotein 1.	Caspase 8; Belongs to the peptidase C14A family.	0.618
GLG1	CCDC88A	ENSOARP00000006158	ENSOARP00000002557	Golgi glycoprotein 1.	Coiled-coil domain containing 88A.	0.780
GLG1	DSC1	ENSOARP00000006158	ENSOARP00000007216	Golgi glycoprotein 1.	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.577