Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX41 | IRF3 | ENSOARP00000005977 | ENSOARP00000014293 | DEAD-box helicase 41. | Interferon regulatory factor 3. | 0.735 |
| DDX41 | IRF7 | ENSOARP00000005977 | ENSOARP00000007094 | DEAD-box helicase 41. | Interferon regulatory factor 7. | 0.471 |
| DDX41 | MAVS | ENSOARP00000005977 | ENSOARP00000000974 | DEAD-box helicase 41. | Mitochondrial antiviral signaling protein. | 0.602 |
| DDX41 | STING1 | ENSOARP00000005977 | ENSOARP00000018530 | DEAD-box helicase 41. | Transmembrane protein 173. | 0.582 |
| DDX41 | TBK1 | ENSOARP00000005977 | ENSOARP00000003587 | DEAD-box helicase 41. | TANK binding kinase 1. | 0.809 |
| DDX41 | TLR3 | ENSOARP00000005977 | ENSOARP00000008645 | DEAD-box helicase 41. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.431 |
| DDX41 | TLR9 | ENSOARP00000005977 | ENSOARP00000006599 | DEAD-box helicase 41. | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). | 0.482 |
| DDX41 | W5P7Y3_SHEEP | ENSOARP00000005977 | ENSOARP00000006537 | DEAD-box helicase 41. | Mab-21 domain-containing protein. | 0.884 |
| IFNAR1 | IRF3 | ENSOARP00000014132 | ENSOARP00000014293 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon regulatory factor 3. | 0.903 |
| IFNAR1 | IRF7 | ENSOARP00000014132 | ENSOARP00000007094 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon regulatory factor 7. | 0.794 |
| IFNAR1 | ISG15 | ENSOARP00000014132 | ENSOARP00000007752 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Uncharacterized protein. | 0.771 |
| IFNAR1 | MAVS | ENSOARP00000014132 | ENSOARP00000000974 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Mitochondrial antiviral signaling protein. | 0.756 |
| IFNAR1 | STING1 | ENSOARP00000014132 | ENSOARP00000018530 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Transmembrane protein 173. | 0.538 |
| IFNAR1 | TBK1 | ENSOARP00000014132 | ENSOARP00000003587 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | TANK binding kinase 1. | 0.750 |
| IFNAR1 | TLR3 | ENSOARP00000014132 | ENSOARP00000008645 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.729 |
| IFNAR1 | TLR9 | ENSOARP00000014132 | ENSOARP00000006599 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). | 0.612 |
| IFNAR1 | W5P7Y3_SHEEP | ENSOARP00000014132 | ENSOARP00000006537 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Mab-21 domain-containing protein. | 0.686 |
| IRF3 | DDX41 | ENSOARP00000014293 | ENSOARP00000005977 | Interferon regulatory factor 3. | DEAD-box helicase 41. | 0.735 |
| IRF3 | IFNAR1 | ENSOARP00000014293 | ENSOARP00000014132 | Interferon regulatory factor 3. | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | 0.903 |
| IRF3 | IRF7 | ENSOARP00000014293 | ENSOARP00000007094 | Interferon regulatory factor 3. | Interferon regulatory factor 7. | 0.980 |
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