STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PALD1Phosphatase domain containing paladin 1. (856 aa)    
Predicted Functional Partners:
ZNF646
Zinc finger protein 646.
      
 0.769
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
   
  
 0.615
MARC1
MOSC domain-containing protein.
      
 0.574
NOTO
Notochord homeobox.
      
 0.533
VASH1
Vasohibin 1.
      
 0.517
STX4
Syntaxin 4; Belongs to the syntaxin family.
      
 0.503
PARP2
Poly [ADP-ribose] polymerase.
      
 0.476
SPINK1
Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.
      
 0.457
ATP2B1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
      
 0.416
MARC2
Mitochondrial amidoxime reducing component 2.
      
 0.414
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.